It is also remarkable that neurocognitive deficits are not specific of BD, and they may be considered as a common dimension across disparate psychiatric disorders, thus a trans-nosological domain (Millan et al., 2015; Vieta, 2016). In this vein, the Research Domain Criteria (RDoc) is an alternative approach with the purpose of conducting research in terms of dimensions, defined by neurobiology and behavioral measures, which cut across traditional diagnostic categories. This framework incorporates genetics, neuroimaging, and cognitive sciences for a new classification of mental disorders (Cuthbert, 2014), where the cognitive system is among the proposed higher order domains. Although this framework was designed to serve templates for research, interestingly it might enrich current DSM diagnoses with more individualized nuances by highlighting factors that mediate or moderate the clinical course and response to treatment. Combining this information, in a hybrid model, might provide a powerful prognostic capacity regarding the course and treatment response as well as help to guide the treatment planning (Yager et al. 2017).

(http://www.autoadmit.com/thread.php?thread_id=3805757&forum_id=2#34748740)