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Nicotine in dads causes dumb psycho kids and grandkids

https://www.the-scientist.com/news-opinion/nicotines-effects...
talented puce genital piercing tanning salon
  10/17/18
A few generations ago, most men smoked. Is that why so many ...
mint aphrodisiac wagecucks
  10/17/18
and they also smoked the preceding 200 years
provocative den
  10/17/18
huge cohort of greatest generation men smokers = boomer beha...
talented puce genital piercing tanning salon
  10/17/18
180. I hope this is true.
aquamarine slippery love of her life
  10/17/18
...
autistic demanding cumskin school
  10/17/18
Flame. There should be more studies like this that look at w...
aquamarine slippery love of her life
  10/17/18
...
autistic demanding cumskin school
  10/17/18
The last line. They probably gave the mice enough nicot...
duck-like pozpig macaca
  10/17/18
that lab is one of the leading e-cig testing labs. i can't ...
talented puce genital piercing tanning salon
  10/17/18
The problem here is dose. Why did not they try "huge d...
ebony mind-boggling mexican
  10/17/18


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Date: October 17th, 2018 2:05 PM
Author: talented puce genital piercing tanning salon

https://www.the-scientist.com/news-opinion/nicotines-effects-passed-on-through-generations-of-mice-64951

Nicotine’s Effects Passed On Through Generations of Mice

Male rodents exposed to nicotine had changes in sperm genome methylation and produced pups and grandpups with abnormal behavior.

Oct 16, 2018

KERRY GRENS

Nicotine can wield its effects on offspring in more ways than from exposures in utero or secondhand smoke: the sperm of mice that ingested nicotine carry epigenetic signatures of that exposure, a study published in PLOS Biology today (October 16) reports. The result might explain why the experiments also found the male mice’s offspring—and grandoffspring—exhibited abnormal behavior and learning impairments.

“Until now, much attention had been focused on the effects of maternal nicotine exposure on their children,” Florida State University’s Pradeep Bhide, who led the study, tells The Boston Globe in an email. “Not much had been known about the effects of paternal smoking on their children and grandchildren. Our study shows that paternal nicotine exposure can be deleterious for the offspring in multiple generations.”

To investigate paternal exposure, Bhide’s team spiked male mice’s drinking water with nicotine for 12 weeks. The researchers then bred those animals with unexposed females, and mated the offspring to produce the third generation.

The second- and third-generation mice underwent a battery of cognitive and behavioral tests to see if their father’s or grandfather’s nicotine exposure had any effect. On some examinations, the mice performed typically, but they didn’t do as well on certain learning tasks as mice whose parent or grandparent had not been given nicotine. The second generation also exhibited hyperactivity and had lower levels of certain neurotransmitters in the brain than the offspring of unexposed animals had.

The results “are consistent with the clinical presentation, putative neurobiological mechanisms, and rate of diagnosis of ADHD and autism,” the authors write in their report.

In search of a possible mechanism for the transgenerational effects of nicotine, the investigators assessed methylation on the sperm genome of exposed and unexposed mice, finding fewer such epigenetic markers in the nicotine-treated animals.

Scientists expressed uncertainty over the ability to extrapolate these results to humans, in part because the mice in the study “were forced to absorb what for them are huge doses of nicotine,” Peter Hajek, director of the Tobacco Dependence Research Unit at Queen Mary University of London, tells Newsweek. “Such studies rarely translate to human smokers.”

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043000)



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Date: October 17th, 2018 2:18 PM
Author: mint aphrodisiac wagecucks

A few generations ago, most men smoked. Is that why so many people are nuts today?

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043105)



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Date: October 17th, 2018 2:23 PM
Author: provocative den

and they also smoked the preceding 200 years

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043143)



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Date: October 17th, 2018 2:23 PM
Author: talented puce genital piercing tanning salon

huge cohort of greatest generation men smokers = boomer behavior

boomers then smoking = genx/millenial behavior, compounded with the damage already done by greatest gen

fewer genx/millenial smokers, but the damage is done

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043147)



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Date: October 17th, 2018 2:20 PM
Author: aquamarine slippery love of her life

180. I hope this is true.

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043117)



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Date: October 17th, 2018 2:25 PM
Author: autistic demanding cumskin school



(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043158)



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Date: October 17th, 2018 2:34 PM
Author: aquamarine slippery love of her life

Flame. There should be more studies like this that look at what men put into their bodies. Also it makes no sense to look at the impact of birth control.

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043230)



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Date: October 17th, 2018 3:05 PM
Author: autistic demanding cumskin school



(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043467)



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Date: October 17th, 2018 3:04 PM
Author: duck-like pozpig macaca

The last line.

They probably gave the mice enough nicotine to equate to a couple cartons a day.

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043460)



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Date: October 17th, 2018 3:38 PM
Author: talented puce genital piercing tanning salon

that lab is one of the leading e-cig testing labs. i can't imagine what incentive they would have to discredit anyone trying to stop the ongoing use of nicotine products

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043681)



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Date: October 17th, 2018 3:10 PM
Author: ebony mind-boggling mexican

The problem here is dose. Why did not they try "huge doses" of caffeine or aspirin instead?

(http://www.autoadmit.com/thread.php?thread_id=4108906&forum_id=2#37043511)